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Sharadha Dayalan Naidu
Sharadha Dayalan Naidu
Johns Hopkins University, University of Dundee
Verified email at dundee.ac.uk
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
106912021
Regulation of the mammalian heat shock factor 1
S Dayalan Naidu, AT Dinkova‐Kostova
The FEBS journal 284 (11), 1606-1627, 2017
1712017
Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection
SD Naidu, RV Kostov, AT Dinkova-Kostova
Trends in pharmacological sciences 36 (1), 6-14, 2015
1382015
KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients
L Quinti, S Dayalan Naidu, U Träger, X Chen, K Kegel-Gleason, D Llères, ...
Proceedings of the National Academy of Sciences 114 (23), E4676-E4685, 2017
1212017
KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy
T Shekh-Ahmad, R Eckel, S Dayalan Naidu, M Higgins, M Yamamoto, ...
Brain 141 (5), 1390-1403, 2018
1062018
SIRT2-and NRF2-targeting thiazole-containing compound with therapeutic activity in Huntington's disease models
L Quinti, M Casale, S Moniot, TF Pais, MJ Van Kanegan, LS Kaltenbach, ...
Cell chemical biology 23 (7), 849-861, 2016
832016
KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease
S Dayalan Naidu, AT Dinkova-Kostova
Open biology 10 (6), 200105, 2020
822020
Heat shock factor 1 is a substrate for p38 mitogen-activated protein kinases
S Dayalan Naidu, C Sutherland, Y Zhang, A Risco, L de la Vega, ...
Molecular and cellular biology 36 (18), 2403-2417, 2016
812016
Activation of Nrf2 signaling augments vesicular stomatitis virus oncolysis via autophagy-driven suppression of antiviral immunity
D Olagnier, RR Lababidi, SB Hadj, A Sze, Y Liu, SD Naidu, M Ferrari, ...
Molecular Therapy 25 (8), 1900-1916, 2017
782017
C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape
S Dayalan Naidu, A Muramatsu, R Saito, S Asami, T Honda, T Hosoya, ...
Scientific reports 8 (1), 8037, 2018
682018
Phenethyl isothiocyanate, a dual activator of transcription factors NRF2 and HSF1
S Dayalan Naidu, T Suzuki, M Yamamoto, JW Fahey, ...
Molecular nutrition & food research 62 (18), 1700908, 2018
512018
Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response
DG Ryan, EV Knatko, AM Casey, JL Hukelmann, SD Naidu, AJ Brenes, ...
Iscience 25 (2), 2022
502022
Transcription factors NRF2 and HSF1 have opposing functions in autophagy
S Dayalan Naidu, D Dikovskaya, E Gaurilcikaite, EV Knatko, ZR Healy, ...
Scientific reports 7 (1), 11023, 2017
362017
Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation
Y Zhang, S Dayalan Naidu, K Samarasinghe, GC Van Hecke, A Pheely, ...
British journal of cancer 110 (1), 71-82, 2014
322014
Downregulation of Keap1 confers features of a fasted metabolic state
EV Knatko, MH Tatham, Y Zhang, C Castro, M Higgins, SD Naidu, ...
IScience 23 (10), 2020
222020
Guidelines for the use and interpretation of assays for monitoring autophagy 1
D Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
Autophagy 17 (1), 1-382, 2021
202021
Phenyl bis-sulfonamide Keap1-Nrf2 protein–protein interaction inhibitors with an alternative binding mode
N Georgakopoulos, S Talapatra, D Dikovskaya, S Dayalan Naidu, ...
Journal of Medicinal Chemistry 65 (10), 7380-7398, 2022
182022
The cell-permeable derivative of the immunoregulatory metabolite itaconate, 4-octyl itaconate, is anti-fibrotic in systemic sclerosis
J Henderson, S Dayalan Naidu, AT Dinkova-Kostova, S Przyborski, ...
Cells 10 (8), 2053, 2021
142021
Omaveloxolone (SkyclarysTM) for patients with Friedreich’s ataxia
SD Naidu, AT Dinkova-Kostova
Trends in Pharmacological Sciences, 2023
122023
The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2
SD Naidu, T Suzuki, D Dikovskaya, EV Knatko, M Higgins, M Sato, ...
Iscience 25 (1), 2022
122022
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