An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex Y Zhang, K Chen, SA Sloan, ML Bennett, AR Scholze, S O'Keeffe, ... Journal of neuroscience 34 (36), 11929-11947, 2014 | 4975 | 2014 |
Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators Q Yan, SM Weyn-Vanhentenryck, J Wu, SA Sloan, Y Zhang, K Chen, ... Proceedings of the National Academy of Sciences 112 (11), 3445-3450, 2015 | 168 | 2015 |
Dynamic transcriptional responses to injury of regenerative and non-regenerative cardiomyocytes revealed by single-nucleus RNA sequencing M Cui, Z Wang, K Chen, AM Shah, W Tan, L Duan, E Sanchez-Ortiz, H Li, ... Developmental cell 53 (1), 102-116. e8, 2020 | 147 | 2020 |
Exosomes Mediate Epithelium–Mesenchyme Crosstalk in Organ Development JJM Nan Jiang, Lusai Xiang, Ling He, Guodong Yang, Jinxuan Zheng, Chenglin ... ACS Nano 11, 7736−7746, 2017 | 127 | 2017 |
RNA-seq characterization of spinal cord injury transcriptome in acute/subacute phases: a resource for understanding the pathology at the systems level K Chen, S Deng, H Lu, Y Zheng, G Yang, D Kim, Q Cao, JQ Wu PloS one 8 (8), e72567, 2013 | 109 | 2013 |
The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development CM Masaki Miyazaki, Kazuko Miyazaki, Kenian Chen, Yi Jin, Jacob Turner ... Immunity 46 (5), 818–834, 2017 | 93 | 2017 |
Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance M Cui, A Atmanli, MG Morales, W Tan, K Chen, X Xiao, L Xu, N Liu, ... Nature communications 12 (1), 5270, 2021 | 92 | 2021 |
Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice AC Chai, M Cui, F Chemello, H Li, K Chen, W Tan, A Atmanli, ... Nature medicine 29 (2), 401-411, 2023 | 87 | 2023 |
Active enhancer and chromatin accessibility landscapes chart the regulatory network of primary multiple myeloma Y Jin, K Chen, A De Paepe, E Hellqvist, AD Krstic, L Metang, ... Blood, The Journal of the American Society of Hematology 131 (19), 2138-2150, 2018 | 83 | 2018 |
Comprehensive identification of long non-coding RNAs in purified cell types from the brain reveals functional LncRNA in OPC fate determination X Dong, K Chen, R Cuevas-Diaz Duran, Y You, SA Sloan, Y Zhang, ... PLoS genetics 11 (12), e1005669, 2015 | 81 | 2015 |
Mice with increased numbers of polyploid hepatocytes maintain regenerative capacity but develop fewer hepatocellular carcinomas following chronic liver injury YH Lin, S Zhang, M Zhu, T Lu, K Chen, Z Wen, S Wang, G Xiao, D Luo, ... Gastroenterology 158 (6), 1698-1712. e14, 2020 | 75 | 2020 |
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy T Nishiyama, Y Zhang, M Cui, H Li, E Sanchez-Ortiz, JR McAnally, W Tan, ... Science translational medicine 14 (672), eade1633, 2022 | 74 | 2022 |
Ablation of CaMKIIδ oxidation by CRISPR-Cas9 base editing as a therapy for cardiac disease S Lebek, F Chemello, XM Caravia, W Tan, H Li, K Chen, L Xu, N Liu, ... Science 379 (6628), 179-185, 2023 | 60 | 2023 |
Parenchymal and stromal tissue regeneration of tooth organ by pivotal signals reinstated in decellularized matrix L He, J Zhou, M Chen, CS Lin, SG Kim, Y Zhou, L Xiang, M Xie, H Bai, ... Nature materials 18 (6), 627-637, 2019 | 60 | 2019 |
Alternative splicing: An important mechanism in stem cell biology K Chen, X Dai, J Wu World journal of stem cells 7 (1), 1, 2015 | 59 | 2015 |
The histone reader PHF7 cooperates with the SWI/SNF complex at cardiac super enhancers to promote direct reprogramming GA Garry, S Bezprozvannaya, K Chen, H Zhou, H Hashimoto, ... Nature cell biology 23 (5), 467-475, 2021 | 49 | 2021 |
The transcription factor E2A activates multiple enhancers that drive Rag expression in developing T and B cells K Miyazaki, H Watanabe, G Yoshikawa, K Chen, R Hidaka, Y Aitani, ... Science Immunology 5 (51), eabb1455, 2020 | 48 | 2020 |
Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes Z Wang, K Chen, Y Jia, JC Chuang, X Sun, YH Lin, C Celen, L Li, ... Nature cancer 1 (9), 909-922, 2020 | 46 | 2020 |
Twist2 amplification in rhabdomyosarcoma represses myogenesis and promotes oncogenesis by redirecting MyoD DNA binding S Li, K Chen, Y Zhang, SD Barnes, P Jaichander, Y Zheng, M Hassan, ... Genes & Development, 2019 | 34 | 2019 |
Plasma cell fate is orchestrated by elaborate changes in genome compartmentalization and inter-chromosomal hubs A Bortnick, Z He, M Aubrey, V Chandra, M Denholtz, K Chen, YC Lin, ... Cell reports 31 (1), 2020 | 28 | 2020 |