| Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury BS Slusher, JJ Vornov, AG Thomas, PD Hurn, I Harukuni, A Bhardwaj, ... Nature medicine 5 (12), 1396-1402, 1999 | 370 | 1999 |
| Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures JJ Vornov, RC Tasker, JT Coyle Experimental neurology 114 (1), 11-22, 1991 | 194 | 1991 |
| We're Not “DON” Yet: Optimal Dosing and Prodrug Delivery of 6-Diazo-5-oxo-L-norleucine KM Lemberg, JJ Vornov, R Rais, BS Slusher Molecular cancer therapeutics 17 (9), 1824-1832, 2018 | 180 | 2018 |
| The regional vulnerability to hypoglycemia-induced neurotoxicity in organotypic hippocampal culture: protection by early tetrodotoxin or delayed MK-801 RC Tasker, JT Coyle, JJ Vornov Journal of Neuroscience 12 (11), 4298-4308, 1992 | 155 | 1992 |
| Inhibition of virus-induced neuronal apoptosis by Bax J Lewis, GA Oyler, K Ueno, YR Fannjiang, BN Chau, J Vornov, ... Nature medicine 5 (7), 832-835, 1999 | 136 | 1999 |
| Delayed protection by MK-801 and tetrodotoxin in a rat organotypic hippocampal culture model of ischemia. JJ Vornov, RC Tasker, JT Coyle Stroke 25 (2), 457-464, 1994 | 131 | 1994 |
| Pharmacokinetics and clinical pharmacodynamics of the new propofol prodrug GPI 15715 in volunteers. J Fechner, H Ihmsen, D Hatterscheid, C Schiessl, JJ Vornov, E Burak, ... Anesthesiology 99 (2), 303-313, 2003 | 120* | 2003 |
| Protective effects of extracellular acidosis and blockade of sodium/hydrogen ion exchange during recovery from metabolic inhibition in neuronal tissue culture JJ Vornov, AG Thomas, D Jo Journal of neurochemistry 67 (6), 2379-2389, 1996 | 114 | 1996 |
| Comparative pharmacokinetics and pharmacodynamics of the new propofol prodrug GPI 15715 and propofol emulsion. J Fechner, H Ihmsen, D Hatterscheid, C Jeleazcov, C Schiessl, JJ Vornov, ... Anesthesiology 101 (3), 626-639, 2004 | 96 | 2004 |
| Selective release ofN-acetylaspartylglutamate from rat optic nerve terminals in vivo G Tsai, BL Stauch, JJ Vornov, JK Deshpande, JT Coyle Brain research 518 (1-2), 313-316, 1990 | 87 | 1990 |
| Glutamate neurotoxicity and the inhibition of protein synthesis in the hippocampal slice JJ Vornov, JT Coyle Journal of neurochemistry 56 (3), 996-1006, 1991 | 84 | 1991 |
| AQUAVAN injection, a water-soluble prodrug of propofol, as a bolus injection: a phase I dose-escalation comparison with DIPRIVAN (part 1): pharmacokinetics. E Gibiansky, MM Struys, L Gibiansky, AL Vanluchene, J Vornov, ... Anesthesiology 103 (4), 718-729, 2005 | 79 | 2005 |
| Toxic NMDA‐receptor activation occurs during recovery in a tissue culture model of ischemia JJ Vornov Journal of neurochemistry 65 (4), 1681-1691, 1995 | 78 | 1995 |
| The central nervous system effects, pharmacokinetics and safety of the NAALADase‐inhibitor GPI 5693 JP Van Der Post, SJ De Visser, ML De Kam, M Woelfler, DC Hilt, J Vornov, ... British journal of clinical pharmacology 60 (2), 128-136, 2005 | 74 | 2005 |
| Pharmacokinetics and pharmacodynamics of the new propofol prodrug GPI 15715 in rates M Schywalsky, H Ihmsen, A Tzabazis, J Fechner, E Burak, J Vornov, ... European journal of anaesthesiology 20 (3), 182-190, 2003 | 74 | 2003 |
| Regional vulnerability to endogenous and exogenous oxidative stress in organotypic hippocampal culture JJ Vornov, J Park, AG Thomas Experimental neurology 149 (1), 109-122, 1998 | 73 | 1998 |
| AQUAVAN injection, a water-soluble prodrug of propofol, as a bolus injection: a phase I dose-escalation comparison with DIPRIVAN (part 2): pharmacodynamics and safety. MM Struys, AL Vanluchene, E Gibiansky, L Gibiansky, J Vornov, ... Anesthesiology 103 (4), 730-743, 2005 | 72 | 2005 |
| Neurotoxicity of acute glutamate transport blockade depends on coactivation of both NMDA and AMPA/kainate receptors in organotypic hippocampal cultures JJ Vornov, RC Tasker, J Park Experimental neurology 133 (1), 7-17, 1995 | 63 | 1995 |
| Peripheral neuropathy induced by microtubule-targeted chemotherapies: insights into acute injury and long-term recovery KM Wozniak, JJ Vornov, Y Wu, Y Liu, VA Carozzi, V Rodriguez-Menendez, ... Cancer research 78 (3), 817-829, 2018 | 62 | 2018 |
| N-acetylated α-linked acidic dipeptidase converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin AG Thomas, JJ Vornov, JL Olkowski, AT Merion, BS Slusher Journal of Pharmacology and Experimental Therapeutics 295 (1), 16-22, 2000 | 60 | 2000 |
Barbara S. SlusherProfessor of Neurology, Psychiatry, Neuroscience, Medicine, Oncology, Johns Hopkins UniversityVerified email at jhmi.edu
