| Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-β in Alzheimer's disease brain but not in transgenic mouse brain WE Klunk, BJ Lopresti, MD Ikonomovic, IM Lefterov, RP Koldamova, ... Journal of Neuroscience 25 (46), 10598-10606, 2005 | 458 | 2005 |
| Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice R Koldamova, M Staufenbiel, I Lefterov Journal of Biological Chemistry 280 (52), 43224-43235, 2005 | 415 | 2005 |
| The liver X receptor ligand T0901317 decreases amyloid β production in vitro and in a mouse model of Alzheimer's disease RP Koldamova, IM Lefterov, M Staufenbiel, D Wolfe, S Huang, ... Journal of Biological Chemistry 280 (6), 4079-4088, 2005 | 322 | 2005 |
| 22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid β secretion RP Koldamova, IM Lefterov, MD Ikonomovic, J Skoko, PI Lefterov, ... Journal of Biological Chemistry 278 (15), 13244-13256, 2003 | 296 | 2003 |
| Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice NF Fitz, A Cronican, T Pham, A Fogg, AH Fauq, R Chapman, I Lefterov, ... Journal of Neuroscience 30 (20), 6862-6872, 2010 | 199 | 2010 |
| The role of APOE and TREM2 in Alzheimer′ s disease—current understanding and perspectives CM Wolfe, NF Fitz, KN Nam, I Lefterov, R Koldamova International journal of molecular sciences 20 (1), 81, 2018 | 166 | 2018 |
| Apolipoprotein AI directly interacts with amyloid precursor protein and inhibits Aβ aggregation and toxicity RP Koldamova, IM Lefterov, MI Lefterova, JS Lazo Biochemistry 40 (12), 3553-3560, 2001 | 157 | 2001 |
| Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice NF Fitz, AA Cronican, M Saleem, AH Fauq, R Chapman, I Lefterov, ... Journal of Neuroscience 32 (38), 13125-13136, 2012 | 149 | 2012 |
| ATP-binding cassette transporter A1: from metabolism to neurodegeneration R Koldamova, NF Fitz, I Lefterov Neurobiology of disease 72, 13-21, 2014 | 140 | 2014 |
| Apolipoprotein AI deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1ΔE9 mice I Lefterov, NF Fitz, AA Cronican, A Fogg, P Lefterov, R Kodali, R Wetzel, ... Journal of Biological Chemistry 285 (47), 36945-36957, 2010 | 137 | 2010 |
| The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration R Koldamova, NF Fitz, I Lefterov Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010 | 112 | 2010 |
| Heavy chronic intermittent ethanol exposure alters small noncoding RNAs in mouse sperm and epididymosomes GR Rompala, A Mounier, CM Wolfe, Q Lin, I Lefterov, GE Homanics Frontiers in genetics 9, 32, 2018 | 107 | 2018 |
| Expression profiling in APP23 mouse brain: inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment I Lefterov, A Bookout, Z Wang, M Staufenbiel, D Mangelsdorf, ... Molecular neurodegeneration 2, 1-15, 2007 | 104 | 2007 |
| Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic AA Cronican, NF Fitz, A Carter, M Saleem, S Shiva, A Barchowsky, ... PloS one 8 (2), e53478, 2013 | 101 | 2013 |
| Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice KN Nam, A Mounier, CM Wolfe, NF Fitz, AY Carter, EL Castranio, ... Scientific reports 7 (1), 4307, 2017 | 85 | 2017 |
| Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration R Koldamova, J Schug, M Lefterova, AA Cronican, NF Fitz, FA Davenport, ... Neurobiology of disease 63, 107-114, 2014 | 81 | 2014 |
| Role of LXR and ABCA1 in the pathogenesis of Alzheimer's disease-implications for a new therapeutic approach R Koldamova, I Lefterov Current Alzheimer research 4 (2), 171-178, 2007 | 72 | 2007 |
| Bexarotene-activated retinoid X receptors regulate neuronal differentiation and dendritic complexity A Mounier, D Georgiev, KN Nam, NF Fitz, EL Castranio, CM Wolfe, ... Journal of Neuroscience 35 (34), 11862-11876, 2015 | 71 | 2015 |
| Memory Deficits in APP23/Abca1+/− Mice Correlate with the Level of Aβ Oligomers I Lefterov, NF Fitz, A Cronican, P Lefterov, M Staufenbiel, R Koldamova ASN neuro 1 (2), AN20090015, 2009 | 71 | 2009 |
| Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease NF Fitz, KN Nam, CM Wolfe, F Letronne, BE Playso, BE Iordanova, ... Nature communications 12 (1), 3416, 2021 | 70 | 2021 |
