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Lesley Ann Kane
Lesley Ann Kane
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Year
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
M Lazarou, DA Sliter, LA Kane, SA Sarraf, C Wang, JL Burman, ...
Nature 524 (7565), 309-314, 2015
23462015
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
SM Jin, M Lazarou, C Wang, LA Kane, DP Narendra, RJ Youle
Journal of Cell Biology 191 (5), 933-942, 2010
13652010
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
LA Kane, M Lazarou, AI Fogel, Y Li, K Yamano, SA Sarraf, S Banerjee, ...
Journal of Cell Biology 205 (2), 143-153, 2014
12372014
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
D Narendra, LA Kane, DN Hauser, IM Fearnley, RJ Youle
Autophagy 6 (8), 1090-1106, 2010
8422010
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin
M Lazarou, SM Jin, LA Kane, RJ Youle
Developmental cell 22 (2), 320-333, 2012
6782012
Preparation of proteins and peptides for mass spectrometry analysis in a bottom‐up proteomics workflow
RL Gundry, MY White, CI Murray, LA Kane, Q Fu, BA Stanley, JE Van Eyk
Current protocols in molecular biology 90 (1), 10.25. 1-10.25. 23, 2010
4072010
High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy
SA Hasson, LA Kane, K Yamano, CH Huang, DA Sliter, E Buehler, ...
Nature 504 (7479), 291-295, 2013
3852013
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys
MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, DJ Kim, ...
Science translational medicine 12 (545), eaay1359, 2020
2182020
Proteomic analysis of pharmacological preconditioning novel protein targets converge to mitochondrial metabolism pathways
DK Arrell, ST Elliott, LA Kane, Y Guo, YH Ko, PL Pedersen, J Robinson, ...
Circulation research 99 (7), 706-714, 2006
1592006
Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling
JJ Sims, F Scavone, EM Cooper, LA Kane, RJ Youle, JD Boeke, ...
Nature methods 9 (3), 303-309, 2012
1362012
Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts
G Agnetti, N Kaludercic, LA Kane, ST Elliott, Y Guo, K Chakir, ...
Circulation: Cardiovascular Genetics 3 (1), 78-87, 2010
1292010
Highly Divergent Mitochondrial ATP Synthase Complexes in Tetrahymena thermophila
P Balabaskaran Nina, NV Dudkina, LA Kane, JE van Eyk, EJ Boekema, ...
PLoS biology 8 (7), e1000418, 2010
892010
Phosphorylation of the F1Fo ATP Synthase β Subunit Functional and Structural Consequences Assessed in a Model System
LA Kane, MJ Youngman, RE Jensen, JE Van Eyk
Circulation research 106 (3), 504-513, 2010
702010
Site-mapping of in vitro S-nitrosation in cardiac mitochondria: implications for cardioprotection
CI Murray, LA Kane, H Uhrigshardt, SB Wang, JE Van Eyk
Molecular & Cellular Proteomics 10 (3), 2011
662011
Post-translational modifications of ATP synthase in the heart: biology and function
LA Kane, JE Van Eyk
Journal of bioenergetics and biomembranes 41, 145-150, 2009
602009
Mitochondrial fission and fusion and their roles in the heart
LA Kane, RJ Youle
Journal of molecular medicine 88, 971-979, 2010
522010
PINK1 and Parkin flag Miro to direct mitochondrial traffic
LA Kane, RJ Youle
Cell 147 (4), 721-723, 2011
432011
Optimization of paper bridge loading for 2‐DE analysis in the basic pH region: Application to the mitochondrial subproteome
LA Kane, CK Yung, G Agnetti, I Neverova, JE Van Eyk
Proteomics 6 (21), 5683-5687, 2006
422006
Proteomic technologies in the study of kinases: novel tools for the investigation of PKC in the heart
G Agnetti, LA Kane, C Guarnieri, CM Caldarera, JE Van Eyk
Pharmacological research 55 (6), 511-522, 2007
382007
Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth-and stress-dependent fashion
X Pan, LA Kane, JE Van Eyk, PA Coulombe
Journal of Biological Chemistry 286 (49), 42403-42413, 2011
372011
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Articles 1–20