The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy M Lazarou, DA Sliter, LA Kane, SA Sarraf, C Wang, JL Burman, ... Nature 524 (7565), 309-314, 2015 | 2346 | 2015 |
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL SM Jin, M Lazarou, C Wang, LA Kane, DP Narendra, RJ Youle Journal of Cell Biology 191 (5), 933-942, 2010 | 1365 | 2010 |
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity LA Kane, M Lazarou, AI Fogel, Y Li, K Yamano, SA Sarraf, S Banerjee, ... Journal of Cell Biology 205 (2), 143-153, 2014 | 1237 | 2014 |
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both D Narendra, LA Kane, DN Hauser, IM Fearnley, RJ Youle Autophagy 6 (8), 1090-1106, 2010 | 842 | 2010 |
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin M Lazarou, SM Jin, LA Kane, RJ Youle Developmental cell 22 (2), 320-333, 2012 | 678 | 2012 |
Preparation of proteins and peptides for mass spectrometry analysis in a bottom‐up proteomics workflow RL Gundry, MY White, CI Murray, LA Kane, Q Fu, BA Stanley, JE Van Eyk Current protocols in molecular biology 90 (1), 10.25. 1-10.25. 23, 2010 | 407 | 2010 |
High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy SA Hasson, LA Kane, K Yamano, CH Huang, DA Sliter, E Buehler, ... Nature 504 (7479), 291-295, 2013 | 385 | 2013 |
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, DJ Kim, ... Science translational medicine 12 (545), eaay1359, 2020 | 218 | 2020 |
Proteomic analysis of pharmacological preconditioning novel protein targets converge to mitochondrial metabolism pathways DK Arrell, ST Elliott, LA Kane, Y Guo, YH Ko, PL Pedersen, J Robinson, ... Circulation research 99 (7), 706-714, 2006 | 159 | 2006 |
Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling JJ Sims, F Scavone, EM Cooper, LA Kane, RJ Youle, JD Boeke, ... Nature methods 9 (3), 303-309, 2012 | 136 | 2012 |
Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts G Agnetti, N Kaludercic, LA Kane, ST Elliott, Y Guo, K Chakir, ... Circulation: Cardiovascular Genetics 3 (1), 78-87, 2010 | 129 | 2010 |
Highly Divergent Mitochondrial ATP Synthase Complexes in Tetrahymena thermophila P Balabaskaran Nina, NV Dudkina, LA Kane, JE van Eyk, EJ Boekema, ... PLoS biology 8 (7), e1000418, 2010 | 89 | 2010 |
Phosphorylation of the F1Fo ATP Synthase β Subunit Functional and Structural Consequences Assessed in a Model System LA Kane, MJ Youngman, RE Jensen, JE Van Eyk Circulation research 106 (3), 504-513, 2010 | 70 | 2010 |
Site-mapping of in vitro S-nitrosation in cardiac mitochondria: implications for cardioprotection CI Murray, LA Kane, H Uhrigshardt, SB Wang, JE Van Eyk Molecular & Cellular Proteomics 10 (3), 2011 | 66 | 2011 |
Post-translational modifications of ATP synthase in the heart: biology and function LA Kane, JE Van Eyk Journal of bioenergetics and biomembranes 41, 145-150, 2009 | 60 | 2009 |
Mitochondrial fission and fusion and their roles in the heart LA Kane, RJ Youle Journal of molecular medicine 88, 971-979, 2010 | 52 | 2010 |
PINK1 and Parkin flag Miro to direct mitochondrial traffic LA Kane, RJ Youle Cell 147 (4), 721-723, 2011 | 43 | 2011 |
Optimization of paper bridge loading for 2‐DE analysis in the basic pH region: Application to the mitochondrial subproteome LA Kane, CK Yung, G Agnetti, I Neverova, JE Van Eyk Proteomics 6 (21), 5683-5687, 2006 | 42 | 2006 |
Proteomic technologies in the study of kinases: novel tools for the investigation of PKC in the heart G Agnetti, LA Kane, C Guarnieri, CM Caldarera, JE Van Eyk Pharmacological research 55 (6), 511-522, 2007 | 38 | 2007 |
Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth-and stress-dependent fashion X Pan, LA Kane, JE Van Eyk, PA Coulombe Journal of Biological Chemistry 286 (49), 42403-42413, 2011 | 37 | 2011 |