Ee Sin Chen
Ee Sin Chen
Assistant Professor, Dept of Biochemistry, Yong Loo Lin Sch of Medicine, National University of
Verified email at - Homepage
Cited by
Cited by
Comprehensive analysis of heterochromatin-and RNAi-mediated epigenetic control of the fission yeast genome
HP Cam, T Sugiyama, ES Chen, X Chen, PC FitzGerald, SIS Grewal
Nature genetics 37 (8), 809-819, 2005
Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast
K Takahashi, ES Chen, M Yanagida
Science 288 (5474), 2215-2219, 2000
Cell cycle control of centromeric repeat transcription and heterochromatin assembly
ES Chen, K Zhang, E Nicolas, HP Cam, M Zofall, SIS Grewal
Nature 451 (7179), 734-737, 2008
A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast
ES Chen, S Saitoh, M Yanagida, K Takahashi
Molecular cell 11 (1), 175-187, 2003
Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin
FE Reyes-Turcu, K Zhang, M Zofall, E Chen, SIS Grewal
Nature structural & molecular biology 18 (10), 1132-1138, 2011
Ribonuclease activity of Dis3 is required for mitotic progression and provides a possible link between heterochromatin and kinetochore function
H Murakami, DB Goto, T Toda, ES Chen, SI Grewal, RA Martienssen, ...
PLoS One 2 (3), e317, 2007
Transcriptional scaffolds for heterochromatin assembly
HP Cam, ES Chen, SIS Grewal
Cell 136 (4), 610-614, 2009
Cellular factories for coenzyme Q10 production
SQE Lee, TS Tan, M Kawamukai, ES Chen
Microbial cell factories 16, 1-16, 2017
Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin
ES Chen, T Sutani, M Yanagida
Proceedings of the National Academy of Sciences 101 (21), 8078-8083, 2004
NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity
C Li, Y Zhang, Q Yang, F Ye, SY Sun, ES Chen, YC Liou
Scientific reports 6 (1), 18773, 2016
cGAS-STING pathway in oncogenesis and cancer therapeutics
BY Da Hoong, YH Gan, H Liu, ES Chen
Oncotarget 11 (30), 2930, 2020
Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs
RA Jackson, ES Chen
Pharmacology & therapeutics 162, 69-85, 2016
Predicting chemotherapeutic drug combinations through gene network profiling
TTT Nguyen, JKK Chua, KS Seah, SH Koo, JY Yee, EG Yang, KK Lim, ...
Scientific Reports 6 (1), 18658, 2016
Structural and functional specificity of H3K36 methylation
UTF Lam, BKY Tan, JJX Poh, ES Chen
Epigenetics & Chromatin 15 (1), 17, 2022
Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast
Z Tay, RJ Eng, K Sajiki, KK Lim, MY Tang, M Yanagida, ES Chen
PLoS One 8 (1), e55041, 2013
Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast
TTT Nguyen, JSL Lim, RMY Tang, L Zhang, ES Chen
Scientific reports 5 (1), 8400, 2015
SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling
KS Seah, JY Loh, TTT Nguyen, HL Tan, PE Hutchinson, KK Lim, ...
Experimental Cell Research 370 (2), 283-291, 2018
Synthetic combinations of missense polymorphic genetic changes underlying Down syndrome susceptibility
RA Jackson, ML Nguyen, AN Barrett, YY Tan, MA Choolani, ES Chen
Cellular and molecular life sciences 73, 4001-4017, 2016
Human genome meeting 2016: houston, TX, USA. 28 February-2 March 2016
AK Srivastava, Y Wang, R Huang, C Skinner, T Thompson, L Pollard, ...
Human genomics 10, 1-40, 2016
Histone H3 lysine 36 methyltransferase mobilizes NER factors to regulate tolerance against alkylation damage in fission yeast
KK Lim, TTT Nguyen, AY Li, YP Yeo, ES Chen
Nucleic acids research 46 (10), 5061-5074, 2018
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