Comprehensive analysis of heterochromatin-and RNAi-mediated epigenetic control of the fission yeast genome HP Cam, T Sugiyama, ES Chen, X Chen, PC FitzGerald, SIS Grewal Nature genetics 37 (8), 809-819, 2005 | 548 | 2005 |
Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast K Takahashi, ES Chen, M Yanagida Science 288 (5474), 2215-2219, 2000 | 434 | 2000 |
Cell cycle control of centromeric repeat transcription and heterochromatin assembly ES Chen, K Zhang, E Nicolas, HP Cam, M Zofall, SIS Grewal Nature 451 (7179), 734-737, 2008 | 392 | 2008 |
A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast ES Chen, S Saitoh, M Yanagida, K Takahashi Molecular cell 11 (1), 175-187, 2003 | 151 | 2003 |
Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin FE Reyes-Turcu, K Zhang, M Zofall, E Chen, SIS Grewal Nature structural & molecular biology 18 (10), 1132-1138, 2011 | 126 | 2011 |
Ribonuclease activity of Dis3 is required for mitotic progression and provides a possible link between heterochromatin and kinetochore function H Murakami, DB Goto, T Toda, ES Chen, SI Grewal, RA Martienssen, ... PLoS One 2 (3), e317, 2007 | 89 | 2007 |
Transcriptional scaffolds for heterochromatin assembly HP Cam, ES Chen, SIS Grewal Cell 136 (4), 610-614, 2009 | 83 | 2009 |
Cellular factories for coenzyme Q10 production SQE Lee, TS Tan, M Kawamukai, ES Chen Microbial cell factories 16, 1-16, 2017 | 61 | 2017 |
Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin ES Chen, T Sutani, M Yanagida Proceedings of the National Academy of Sciences 101 (21), 8078-8083, 2004 | 50 | 2004 |
NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity C Li, Y Zhang, Q Yang, F Ye, SY Sun, ES Chen, YC Liou Scientific reports 6 (1), 18773, 2016 | 35 | 2016 |
Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs RA Jackson, ES Chen Pharmacology & therapeutics 162, 69-85, 2016 | 33 | 2016 |
cGAS-STING pathway in oncogenesis and cancer therapeutics BY Da Hoong, YH Gan, H Liu, ES Chen Oncotarget 11 (30), 2930, 2020 | 29 | 2020 |
Predicting chemotherapeutic drug combinations through gene network profiling TTT Nguyen, JKK Chua, KS Seah, SH Koo, JY Yee, EG Yang, KK Lim, ... Scientific Reports 6 (1), 1-11, 2016 | 22 | 2016 |
SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling KS Seah, JY Loh, TTT Nguyen, HL Tan, PE Hutchinson, KK Lim, ... Experimental Cell Research 370 (2), 283-291, 2018 | 19 | 2018 |
Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast TTT Nguyen, JSL Lim, RMY Tang, L Zhang, ES Chen Scientific reports 5 (1), 1-10, 2015 | 18 | 2015 |
Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast Z Tay, RJ Eng, K Sajiki, KK Lim, MY Tang, M Yanagida, ES Chen PLoS One 8 (1), e55041, 2013 | 18 | 2013 |
Synthetic combinations of missense polymorphic genetic changes underlying Down syndrome susceptibility RA Jackson, ML Nguyen, AN Barrett, YY Tan, MA Choolani, ES Chen Cellular and molecular life sciences 73, 4001-4017, 2016 | 17 | 2016 |
Prolyl isomerization of the CENP-A N-terminus regulates centromeric integrity in fission yeast HL Tan, KK Lim, Q Yang, JS Fan, AMM Sayed, LS Low, B Ren, TK Lim, ... Nucleic Acids Research 46 (3), 1167-1179, 2018 | 14 | 2018 |
Mutation of histone H3 serine 86 disrupts GATA factor Ams2 expression and precise chromosome segregation in fission yeast KK Lim, TYR Ong, YR Tan, EG Yang, B Ren, KS Seah, Z Yang, TS Tan, ... Scientific reports 5 (1), 1-11, 2015 | 14 | 2015 |
Structural and functional specificity of H3K36 methylation UTF Lam, BKY Tan, JJX Poh, ES Chen Epigenetics & Chromatin 15 (1), 17, 2022 | 13 | 2022 |