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Yuanyu Huang
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Therapeutic siRNA: state of the art
B Hu, L Zhong, Y Weng, L Peng, Y Huang, Y Zhao, XJ Liang
Signal transduction and targeted therapy 5 (1), 101, 2020
8672020
Enhanced gene delivery and siRNA silencing by gold nanoparticles coated with charge-reversal polyelectrolyte
S Guo, Y Huang, Q Jiang, Y Sun, L Deng, Z Liang, Q Du, J Xing, Y Zhao, ...
ACS nano 4 (9), 5505-5511, 2010
4602010
Preclinical and clinical advances of GalNAc-decorated nucleic acid therapeutics
Y Huang
Molecular Therapy-Nucleic Acids 6, 116-132, 2017
2872017
The challenge and prospect of mRNA therapeutics landscape
Y Weng, C Li, T Yang, B Hu, M Zhang, S Guo, H Xiao, XJ Liang, Y Huang
Biotechnology advances 40, 107534, 2020
2582020
RNAi therapeutic and its innovative biotechnological evolution
Y Weng, H Xiao, J Zhang, XJ Liang, Y Huang
Biotechnology advances 37 (5), 801-825, 2019
2552019
Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment
R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu, L Wang, T Sun, N Li, L Han, ...
Chinese chemical letters 34 (2), 107518, 2023
2182023
Multifunctional aptamer-based nanoparticles for targeted drug delivery to circumvent cancer resistance
J Liu, T Wei, J Zhao, Y Huang, H Deng, A Kumar, C Wang, Z Liang, X Ma, ...
Biomaterials 91, 44-56, 2016
2112016
Adaptive amphiphilic dendrimer‐based nanoassemblies as robust and versatile siRNA delivery systems
X Liu, J Zhou, T Yu, C Chen, Q Cheng, K Sengupta, Y Huang, H Li, C Liu, ...
Angewandte Chemie International Edition 53 (44), 11822-11827, 2014
2072014
Bioinspired exosome-like therapeutics and delivery nanoplatforms
M Lu, Y Huang
Biomaterials 242, 119925, 2020
1962020
An estrogen receptor α suppressor, microRNA‐22, is downregulated in estrogen receptor α‐positive human breast cancer cell lines and clinical samples
J Xiong, D Yu, N Wei, H Fu, T Cai, Y Huang, C Wu, X Zheng, Q Du, D Lin, ...
The FEBS journal 277 (7), 1684-1694, 2010
1922010
Functionalized nanoscale micelles improve drug delivery for cancer therapy in vitro and in vivo
T Wei, J Liu, H Ma, Q Cheng, Y Huang, J Zhao, S Huo, X Xue, Z Liang, ...
Nano letters 13 (6), 2528-2534, 2013
1842013
Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice
J Zhou, CP Neff, X Liu, J Zhang, H Li, DD Smith, P Swiderski, T Aboellail, ...
Molecular Therapy 19 (12), 2228-2238, 2011
1832011
A dual targeting dendrimer-mediated siRNA delivery system for effective gene silencing in cancer therapy
Y Dong, T Yu, L Ding, E Laurini, Y Huang, M Zhang, Y Weng, S Lin, ...
Journal of the American Chemical Society 140 (47), 16264-16274, 2018
1732018
Elimination pathways of systemically delivered siRNA
Y Huang, J Hong, S Zheng, Y Ding, S Guo, H Zhang, X Zhang, Q Du, ...
Molecular Therapy 19 (2), 381-385, 2011
1642011
Clinical advances of siRNA therapeutics
B Hu, Y Weng, XH Xia, X Liang, Y Huang
The journal of gene medicine 21 (7), e3097, 2019
1532019
Amphiphilic and biodegradable methoxy polyethylene glycol-block-(polycaprolactone-graft-poly (2-(dimethylamino) ethyl methacrylate)) as an effective gene carrier
S Guo, Y Huang, T Wei, W Zhang, W Wang, D Lin, X Zhang, A Kumar, ...
Biomaterials 32 (3), 879-889, 2011
1192011
Membrane‐destabilizing ionizable lipid empowered imaging‐guided siRNA delivery and cancer treatment
S Guo, K Li, B Hu, C Li, M Zhang, A Hussain, X Wang, Q Cheng, F Yang, ...
Exploration 1 (1), 35-49, 2021
1152021
Intracellular cleavable poly (2-dimethylaminoethyl methacrylate) functionalized mesoporous silica nanoparticles for efficient siRNA delivery in vitro and in vivo
D Lin, Q Cheng, Q Jiang, Y Huang, Z Yang, S Han, Y Zhao, S Guo, ...
Nanoscale 5 (10), 4291-4301, 2013
1112013
Enhanced endosomal/lysosomal escape by distearoyl phosphoethanolamine-polycarboxybetaine lipid for systemic delivery of siRNA
Y Li, Q Cheng, Q Jiang, Y Huang, H Liu, Y Zhao, W Cao, G Ma, F Dai, ...
Journal of controlled release 176, 104-114, 2014
1052014
Ultrabright and multicolorful fluorescence of amphiphilic polyethyleneimine polymer dots for efficiently combined imaging and therapy
Y Sun, W Cao, S Li, S Jin, K Hu, L Hu, Y Huang, X Gao, Y Wu, XJ Liang
Scientific reports 3 (1), 3036, 2013
972013
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