Liam Baird
Liam Baird
Assistant Professor
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Cited by
The cytoprotective role of the Keap1–Nrf2 pathway
L Baird, AT Dinkova-Kostova
Archives of toxicology 85, 241-272, 2011
Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration
KM Holmström, L Baird, Y Zhang, I Hargreaves, A Chalasani, JM Land, ...
Biology open 2 (8), 761-770, 2013
Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex
L Baird, D Llères, S Swift, AT Dinkova-Kostova
Proceedings of the National Academy of Sciences 110 (38), 15259-15264, 2013
Characterizations of three major cysteine sensors of Keap1 in stress response
R Saito, T Suzuki, K Hiramoto, S Asami, E Naganuma, H Suda, T Iso, ...
Molecular and cellular biology 36 (2), 271-284, 2016
Molecular mechanism of cellular oxidative stress sensing by Keap1
T Suzuki, A Muramatsu, R Saito, T Iso, T Shibata, K Kuwata, S Kawaguchi, ...
Cell reports 28 (3), 746-758. e4, 2019
Monitoring Keap1–Nrf2 interactions in single live cells
L Baird, S Swift, D Llères, AT Dinkova-Kostova
Biotechnology advances 32 (6), 1133-1144, 2014
Design, synthesis, and evaluation of triazole derivatives that induce Nrf2 dependent gene products and inhibit the Keap1–Nrf2 protein–protein interaction
HC Bertrand, M Schaap, L Baird, ND Georgakopoulos, A Fowkes, ...
Journal of medicinal chemistry 58 (18), 7186-7194, 2015
Absolute amounts and status of the Nrf2-Keap1-Cul3 complex within cells
T Iso, T Suzuki, L Baird, M Yamamoto
Molecular and Cellular Biology 36 (24), 3100-3112, 2016
NRF2 intensifies host defense systems to prevent lung carcinogenesis, but after tumor initiation accelerates malignant cell growth
H Satoh, T Moriguchi, D Saigusa, L Baird, L Yu, H Rokutan, K Igarashi, ...
Cancer research 76 (10), 3088-3096, 2016
Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymes
T Tsujita, V Peirce, L Baird, Y Matsuyama, M Takaku, SV Walsh, JL Griffin, ...
Molecular and cellular biology, 2014
The spatiotemporal regulation of the Keap1–Nrf2 pathway and its importance in cellular bioenergetics
AT Dinkova-Kostova, L Baird, KM Holmström, CJ Meyer, AY Abramov
Biochemical society transactions 43 (4), 602-610, 2015
Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus
T Suzuki, S Seki, K Hiramoto, E Naganuma, EH Kobayashi, A Yamaoka, ...
Nature communications 8 (1), 14577, 2017
Diffusion dynamics of the Keap1–Cullin3 interaction in single live cells
L Baird, AT Dinkova-Kostova
Biochemical and biophysical research communications 433 (1), 58-65, 2013
A homeostatic shift facilitates endoplasmic reticulum proteostasis through transcriptional integration of proteostatic stress response pathways
L Baird, T Tsujita, EH Kobayashi, R Funayama, T Nagashima, ...
Molecular and Cellular Biology 37 (4), e00439-16, 2017
Geldanamycin-derived HSP90 inhibitors are synthetic lethal with NRF2
L Baird, T Suzuki, Y Takahashi, E Hishinuma, D Saigusa, M Yamamoto
Molecular and Cellular Biology, 2020
NRF2-dependent bioactivation of mitomycin C as a novel strategy to target KEAP1-NRF2 pathway activation in human cancer
L Baird, M Yamamoto
Molecular and cellular biology 41 (2), e00473-20, 2021
Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration
KM Holmstrom, L Baird, Y Zhang, I Hargreaves, A Chalasani, JM Land, ...
Biol Open 2 (8), 761-770, 2013
The Keap1-Nrf2 pathway: From mechanism to medical applications
L Baird, M Yamamoto
Oxidative Stress, 125-147, 2020
Discovery of an NRF 1‐specific inducer from a large‐scale chemical library using a direct NRF 1‐protein monitoring system
T Tsujita, L Baird, Y Furusawa, F Katsuoka, Y Hou, S Gotoh, S Kawaguchi, ...
Genes to Cells 20 (7), 563-577, 2015
Hypoxia-sensitive reporter system for high-throughput screening
T Tsujita, S Kawaguchi, T Dan, L Baird, T Miyata, M Yamamoto
The Tohoku Journal of Experimental Medicine 235 (2), 151-159, 2015
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