| The AAA+ superfamily of functionally diverse proteins J Snider, G Thibault, WA Houry Genome biology 9 (4), 216, 2008 | 194 | 2008 |
| The N-terminal zinc binding domain of ClpX is a dimerization domain that modulates the chaperone function UA Wojtyra, G Thibault, A Tuite, WA Houry Journal of biological chemistry 278 (49), 48981-48990, 2003 | 112 | 2003 |
| Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase U Kanjee, I Gutsche, E Alexopoulos, B Zhao, M El Bakkouri, G Thibault, ... The EMBO journal 30 (5), 931-944, 2011 | 103 | 2011 |
| The membrane stress response buffers lethal effects of lipid disequilibrium by reprogramming the protein homeostasis network G Thibault, G Shui, W Kim, GC McAlister, N Ismail, SP Gygi, MR Wenk, ... Molecular cell 48 (1), 16-27, 2012 | 81 | 2012 |
| Futile protein folding cycles in the ER are terminated by the unfolded protein O-mannosylation pathway C Xu, S Wang, G Thibault, DTW Ng Science 340 (6135), 978-981, 2013 | 72 | 2013 |
| Endoplasmic reticulum stress response in yeast and humans H Wu, BSH Ng, G Thibault Bioscience reports 34 (4), 2014 | 67 | 2014 |
| The endoplasmic reticulum-associated degradation pathways of budding yeast G Thibault, DTW Ng Cold Spring Harbor perspectives in biology 4 (12), a013193, 2012 | 59 | 2012 |
| The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway G Thibault, N Ismail, DTW Ng Proceedings of the National Academy of Sciences 108 (51), 20597-20602, 2011 | 56 | 2011 |
| Routing misfolded proteins through the multivesicular body (MVB) pathway protects against proteotoxicity S Wang, G Thibault, DTW Ng Journal of Biological Chemistry 286 (33), 29376-29387, 2011 | 48 | 2011 |
| Specificity in substrate and cofactor recognition by the N-terminal domain of the chaperone ClpX G Thibault, J Yudin, P Wong, V Tsitrin, R Sprangers, R Zhao, WA Houry Proceedings of the National Academy of Sciences 103 (47), 17724-17729, 2006 | 40 | 2006 |
| Large nucleotide‐dependent movement of the N‐terminal domain of the ClpX chaperone G Thibault, Y Tsitrin, T Davidson, A Gribun, WA Houry The EMBO journal 25 (14), 3367-3376, 2006 | 30 | 2006 |
| Dropping in on lipid droplets: insights into cellular stress and cancer P Shyu, XFA Wong, K Crasta, G Thibault Bioscience reports 38 (5), 2018 | 27 | 2018 |
| From the unfolded protein response to metabolic diseases–lipids under the spotlight N Ho, C Xu, G Thibault J Cell Sci 131 (3), jcs199307, 2018 | 25 | 2018 |
| Lipid bilayer stress-activated IRE-1 modulates autophagy during endoplasmic reticulum stress JH Koh, L Wang, C Beaudoin-Chabot, G Thibault J Cell Sci 131 (22), jcs217992, 2018 | 16 | 2018 |
| Role of the N-terminal domain of the chaperone ClpX in the recognition and degradation of lambda phage protein O G Thibault, WA Houry The Journal of Physical Chemistry B 116 (23), 6717-6724, 2012 | 12 | 2012 |
| A role of agrin in maintaining the stability of vascular endothelial growth factor receptor-2 during tumor angiogenesis K Njah, S Chakraborty, B Qiu, S Arumugam, A Raju, AV Pobbati, ... Cell reports 28 (4), 949-965. e7, 2019 | 7 | 2019 |
| Lipid bilayer stress and proteotoxic stress-induced unfolded protein response deploy divergent transcriptional and non-transcriptional programmes XH Fun, G Thibault Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019 | 7 | 2019 |
| Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins PTJ Shyu, BSH Ng, N Ho, R Chaw, YL Seah, C Marvalim, G Thibault Sci Rep 9, 8637, 2019 | 5 | 2019 |
| Deuterated polyunsaturated fatty acids reduce oxidative stress and extend the lifespan of C. elegans C Beaudoin-Chabot, L Wang, AV Smarun, D Vidović, MS Shchepinov, ... Frontiers in physiology 10, 641, 2019 | 3 | 2019 |
| Lipid perturbation compromises UPR-mediated ER homeostasis as a result of premature degradation of membrane proteins BSH Ng, P Shyu, R Chaw, SY Ling, G Thibault bioRxiv, 178947, 2017 | 2 | 2017 |
Walid HouryProfessor of Biochemistry, University of TorontoVerified email at utoronto.ca
