Guillaume Thibault

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Walid HouryProfessor of Biochemistry, University of TorontoVerified email at utoronto.ca
Benjamin NgVerified email at eatobe.com
Haoxi WuUniversity of Colorado BoulderVerified email at colorado.edu
Shaliny RamachandranPostdoctoral researcher, University of OxfordVerified email at oncology.ox.ac.uk
Kaiyin LiuCleveland ClinicVerified email at ccf.org
Markus R WenkDepartment of Biochemistry, National University of SIngaporeVerified email at nus.edu.sg
Woong KimAlkahest IncVerified email at alkahest.com
Guanghou ShuiInstitute of Genetics and Developmental Biology, Chinese Academy of SciencesVerified email at genetics.ac.cn
Graeme McAlisterThermo Fisher ScientificVerified email at thermofisher.com
lei wangUniversity of MiamiVerified email at mail.ustc.edu.cn
Rongmin ZhaoProfessor of Biological Sciences, University of TorontoVerified email at utsc.utoronto.ca
Karen C. CrastaNational University of Singapore, YLL School of MedicineVerified email at nus.edu.sg
Wilson Wen Bin GohSchool of Biological Sciences, Nanyang Technological UniversityVerified email at ntu.edu.sg
Anandhkumar RajuSenior Research Officer/Mouse Models of Human Cancer Unit, IMCBVerified email at imcb.a-star.edu.sg
Sayan ChakrabortyResearch Scientist, Institute of Molecular and Cell Biology (IMCB), A-STAR, Singapore,RosalindVerified email at imcb.a-star.edu.sg
Xiaomeng WangUniversity college London, Manchester University, Newcastle UniversityVerified email at ntu.edu.sg
Wanjin HongInstitute of Molecular and Cell BiologyVerified email at imcb.a-star.edu.sg
Ajaybabu PobbatiCleveland ClinicVerified email at ccf.org
Stefan TaubertAssociate Professor, Medical Genetics, University of British Columbia (UBC)Verified email at cmmt.ubc.ca
Elisabeth KnustProfessor of Cell and Developmental BiologyVerified email at mpi-cbg.de

Guillaume Thibault

Assistant Professor, Nanyang Technological University

Verified email at ntu.edu.sg - Homepage

Lipid Regulation and Cell Stress


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The AAA+ superfamily of functionally diverse proteins J Snider, G Thibault, WA Houry Genome biology 9 (4), 1-8, 2008	232	2008
Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase U Kanjee, I Gutsche, E Alexopoulos, B Zhao, M El Bakkouri, G Thibault, ... The EMBO journal 30 (5), 931-944, 2011	125	2011
The N-terminal zinc binding domain of ClpX is a dimerization domain that modulates the chaperone function UA Wojtyra, G Thibault, A Tuite, WA Houry Journal of biological chemistry 278 (49), 48981-48990, 2003	122	2003
The membrane stress response buffers lethal effects of lipid disequilibrium by reprogramming the protein homeostasis network G Thibault, G Shui, W Kim, GC McAlister, N Ismail, SP Gygi, MR Wenk, ... Molecular cell 48 (1), 16-27, 2012	109	2012
Endoplasmic reticulum stress response in yeast and humans H Wu, BSH Ng, G Thibault Bioscience reports 34 (4), 2014	92	2014
Futile protein folding cycles in the ER are terminated by the unfolded protein O-mannosylation pathway C Xu, S Wang, G Thibault, DTW Ng Science 340 (6135), 978-981, 2013	79	2013
The endoplasmic reticulum-associated degradation pathways of budding yeast G Thibault, DTW Ng Cold Spring Harbor perspectives in biology 4 (12), a013193, 2012	74	2012
The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway G Thibault, N Ismail, DTW Ng Proceedings of the National Academy of Sciences 108 (51), 20597-20602, 2011	68	2011
Routing misfolded proteins through the multivesicular body (MVB) pathway protects against proteotoxicity S Wang, G Thibault, DTW Ng Journal of Biological Chemistry 286 (33), 29376-29387, 2011	54	2011
Specificity in substrate and cofactor recognition by the N-terminal domain of the chaperone ClpX G Thibault, J Yudin, P Wong, V Tsitrin, R Sprangers, R Zhao, WA Houry Proceedings of the National Academy of Sciences 103 (47), 17724-17729, 2006	42	2006
Dropping in on lipid droplets: insights into cellular stress and cancer P Shyu, XFA Wong, K Crasta, G Thibault Bioscience reports 38 (5), 2018	37	2018
From the unfolded protein response to metabolic diseases–lipids under the spotlight N Ho, C Xu, G Thibault Journal of cell science 131 (3), 2018	35	2018
Lipid bilayer stress-activated IRE-1 modulates autophagy during endoplasmic reticulum stress JH Koh, L Wang, C Beaudoin-Chabot, G Thibault Journal of cell science 131 (22), 2018	33	2018
Large nucleotide‐dependent movement of the N‐terminal domain of the ClpX chaperone G Thibault, Y Tsitrin, T Davidson, A Gribun, WA Houry The EMBO journal 25 (14), 3367-3376, 2006	32	2006
Lipid bilayer stress and proteotoxic stress-induced unfolded protein response deploy divergent transcriptional and non-transcriptional programmes XH Fun, G Thibault Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019	26	2019
Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins PTJ Shyu, BSH Ng, N Ho, R Chaw, YL Seah, C Marvalim, G Thibault Sci Rep 9, 8637, 2019	22	2019
A role of agrin in maintaining the stability of vascular endothelial growth factor receptor-2 during tumor angiogenesis K Njah, S Chakraborty, B Qiu, S Arumugam, A Raju, AV Pobbati, ... Cell reports 28 (4), 949-965. e7, 2019	16	2019
Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress N Ho, WS Yap, J Xu, H Wu, JH Koh, WWB Goh, B George, SC Chong, ... Journal of Cell Biology 219 (7), 2020	15	2020
Role of the N-terminal domain of the chaperone ClpX in the recognition and degradation of lambda phage protein O G Thibault, WA Houry The Journal of Physical Chemistry B 116 (23), 6717-6724, 2012	15	2012
Deuterated polyunsaturated fatty acids reduce oxidative stress and extend the lifespan of C. elegans C Beaudoin-Chabot, L Wang, AV Smarun, D Vidović, MS Shchepinov, ... Frontiers in physiology 10, 641, 2019	12	2019

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