Guillaume Thibault

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Walid HouryProfessor of Biochemistry, University of TorontoVerified email at utoronto.ca
Benjamin NgVerified email at eatobe.com
Haoxi WuUniversity of Colorado BoulderVerified email at colorado.edu
lei wangUniversity of MiamiVerified email at mail.ustc.edu.cn
Shaliny RamachandranPostdoctoral researcher, University of OxfordVerified email at oncology.ox.ac.uk
Kaiyin LiuCleveland ClinicVerified email at ccf.org
Markus R WenkDepartment of Biochemistry, National University of SIngaporeVerified email at nus.edu.sg
Woong KimAlkahest IncVerified email at alkahest.com
Guanghou ShuiInstitute of Genetics and Developmental Biology, Chinese Academy of SciencesVerified email at genetics.ac.cn
Graeme McAlisterThermo Fisher ScientificVerified email at thermofisher.com
Wilson Wen Bin GohSchool of Biological Sciences, Nanyang Technological UniversityVerified email at ntu.edu.sg
Karen C. CrastaNational University of Singapore, Yong Loo Lin School of Medicine, Dept of Physiology and NUHSVerified email at nus.edu.sg
Rongmin ZhaoProfessor of Biological Sciences, University of TorontoVerified email at utsc.utoronto.ca
Stefan TaubertAssociate Professor, Medical Genetics, University of British Columbia (UBC)Verified email at cmmt.ubc.ca
Anandhkumar RajuSenior Research Officer/Mouse Models of Human Cancer Unit, IMCBVerified email at imcb.a-star.edu.sg
Sayan ChakrabortyResearch Scientist, Institute of Molecular and Cell Biology (IMCB), A-STAR, Singapore,RosalindVerified email at imcb.a-star.edu.sg
Xiaomeng WangDuke-NUS Medical School, Nanyang Technological University, University college London, ManchesterVerified email at duke-nus.edu.sg
Wanjin HongInstitute of Molecular and Cell BiologyVerified email at imcb.a-star.edu.sg
Ajaybabu PobbatiCleveland ClinicVerified email at ccf.org
ISHIMORI KOICHIROHokkaido UniversityVerified email at sci.hokudai.ac.jp

Guillaume Thibault

Assistant Professor, Nanyang Technological University

Verified email at ntu.edu.sg - Homepage

Lipid Regulation and Cell Stress


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
The AAA+ superfamily of functionally diverse proteins J Snider, G Thibault, WA Houry Genome biology 9 (4), 1-8, 2008	247	2008
Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase U Kanjee, I Gutsche, E Alexopoulos, B Zhao, M El Bakkouri, G Thibault, ... The EMBO journal 30 (5), 931-944, 2011	143	2011
The N-terminal zinc binding domain of ClpX is a dimerization domain that modulates the chaperone function UA Wojtyra, G Thibault, A Tuite, WA Houry Journal of biological chemistry 278 (49), 48981-48990, 2003	133	2003
The membrane stress response buffers lethal effects of lipid disequilibrium by reprogramming the protein homeostasis network G Thibault, G Shui, W Kim, GC McAlister, N Ismail, SP Gygi, MR Wenk, ... Molecular cell 48 (1), 16-27, 2012	125	2012
Endoplasmic reticulum stress response in yeast and humans H Wu, BSH Ng, G Thibault Bioscience reports 34 (4), e00118, 2014	106	2014
Futile protein folding cycles in the ER are terminated by the unfolded protein O-mannosylation pathway C Xu, S Wang, G Thibault, DTW Ng Science 340 (6135), 978-981, 2013	84	2013
The endoplasmic reticulum-associated degradation pathways of budding yeast G Thibault, DTW Ng Cold Spring Harbor perspectives in biology 4 (12), a013193, 2012	78	2012
The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway G Thibault, N Ismail, DTW Ng Proceedings of the National Academy of Sciences 108 (51), 20597-20602, 2011	71	2011
Routing misfolded proteins through the multivesicular body (MVB) pathway protects against proteotoxicity S Wang, G Thibault, DTW Ng Journal of Biological Chemistry 286 (33), 29376-29387, 2011	59	2011
Dropping in on lipid droplets: insights into cellular stress and cancer P Shyu Jr, XFA Wong, K Crasta, G Thibault Bioscience reports 38 (5), BSR20180764, 2018	48	2018
Lipid bilayer stress-activated IRE-1 modulates autophagy during endoplasmic reticulum stress JH Koh, L Wang, C Beaudoin-Chabot, G Thibault Journal of cell science 131 (22), jcs217992, 2018	46	2018
From the unfolded protein response to metabolic diseases–lipids under the spotlight N Ho, C Xu, G Thibault Journal of cell science 131 (3), jcs199307, 2018	44	2018
Specificity in substrate and cofactor recognition by the N-terminal domain of the chaperone ClpX G Thibault, J Yudin, P Wong, V Tsitrin, R Sprangers, R Zhao, WA Houry Proceedings of the National Academy of Sciences 103 (47), 17724-17729, 2006	44	2006
Lipid bilayer stress and proteotoxic stress-induced unfolded protein response deploy divergent transcriptional and non-transcriptional programmes XH Fun, G Thibault Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019	34	2019
Large nucleotide‐dependent movement of the N‐terminal domain of the ClpX chaperone G Thibault, Y Tsitrin, T Davidson, A Gribun, WA Houry The EMBO journal 25 (14), 3367-3376, 2006	34	2006
Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins PTJ Shyu, BSH Ng, N Ho, R Chaw, YL Seah, C Marvalim, G Thibault Sci Rep 9, 8637, 2019	32	2019
Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress N Ho, WS Yap, J Xu, H Wu, JH Koh, WWB Goh, B George, SC Chong, ... Journal of Cell Biology 219 (7), 2020	29	2020
A role of agrin in maintaining the stability of vascular endothelial growth factor receptor-2 during tumor angiogenesis K Njah, S Chakraborty, B Qiu, S Arumugam, A Raju, AV Pobbati, ... Cell reports 28 (4), 949-965. e7, 2019	22	2019
Deuterated polyunsaturated fatty acids reduce oxidative stress and extend the lifespan of C. elegans C Beaudoin-Chabot, L Wang, AV Smarun, D Vidović, MS Shchepinov, ... Frontiers in physiology 10, 641, 2019	18	2019
Role of the N-terminal domain of the chaperone ClpX in the recognition and degradation of lambda phage protein O G Thibault, WA Houry The Journal of Physical Chemistry B 116 (23), 6717-6724, 2012	17	2012

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