Guillaume Thibault
Guillaume Thibault
Verified email at ntu.edu.sg - Homepage
TitleCited byYear
The AAA+ superfamily of functionally diverse proteins
J Snider, G Thibault, WA Houry
Genome biology 9 (4), 216, 2008
1812008
The N-terminal zinc binding domain of ClpX is a dimerization domain that modulates the chaperone function
UA Wojtyra, G Thibault, A Tuite, WA Houry
Journal of biological chemistry 278 (49), 48981-48990, 2003
1072003
Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase
U Kanjee, I Gutsche, E Alexopoulos, B Zhao, M El Bakkouri, G Thibault, ...
The EMBO Journal 30 (5), 931-944, 2011
962011
The membrane stress response buffers lethal effects of lipid disequilibrium by reprogramming the protein homeostasis network
G Thibault, G Shui, W Kim, GC McAlister, N Ismail, SP Gygi, MR Wenk, ...
Molecular cell 48 (1), 16-27, 2012
762012
Futile protein folding cycles in the ER are terminated by the unfolded protein O-mannosylation pathway
C Xu, S Wang, G Thibault, DTW Ng
Science 340 (6135), 978-981, 2013
712013
Endoplasmic reticulum stress response in yeast and humans
H Wu, BSH Ng, G Thibault
Bioscience reports 34 (4), 2014
632014
The endoplasmic reticulum-associated degradation pathways of budding yeast
G Thibault, DTW Ng
Cold Spring Harbor perspectives in biology 4 (12), a013193, 2012
552012
The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway
G Thibault, N Ismail, DTW Ng
Proceedings of the National Academy of Sciences 108 (51), 20597-20602, 2011
522011
Routing misfolded proteins through the multivesicular body (MVB) pathway protects against proteotoxicity
S Wang, G Thibault, DTW Ng
Journal of Biological Chemistry 286 (33), 29376-29387, 2011
462011
Specificity in substrate and cofactor recognition by the N-terminal domain of the chaperone ClpX
G Thibault, J Yudin, P Wong, V Tsitrin, R Sprangers, R Zhao, WA Houry
Proceedings of the National Academy of Sciences 103 (47), 17724-17729, 2006
382006
Large nucleotide‐dependent movement of the N‐terminal domain of the ClpX chaperone
G Thibault, Y Tsitrin, T Davidson, A Gribun, WA Houry
The EMBO journal 25 (14), 3367-3376, 2006
302006
From the unfolded protein response to metabolic diseases–lipids under the spotlight
N Ho, C Xu, G Thibault
J Cell Sci 131 (3), jcs199307, 2018
202018
Lipid bilayer stress-activated IRE-1 modulates autophagy during endoplasmic reticulum stress
JH Koh, L Wang, C Beaudoin-Chabot, G Thibault
J Cell Sci 131 (22), jcs217992, 2018
142018
Dropping in on lipid droplets: insights into cellular stress and cancer
P Shyu, XFA Wong, K Crasta, G Thibault
Bioscience reports 38 (5), 2018
142018
Role of the N-terminal domain of the chaperone ClpX in the recognition and degradation of lambda phage protein O
G Thibault, WA Houry
The Journal of Physical Chemistry B 116 (23), 6717-6724, 2012
122012
A role of agrin in maintaining the stability of vascular endothelial growth factor receptor-2 during tumor angiogenesis
K Njah, S Chakraborty, B Qiu, S Arumugam, A Raju, AV Pobbati, ...
Cell reports 28 (4), 949-965. e7, 2019
62019
Lipid bilayer stress and proteotoxic stress-induced unfolded protein response deploy divergent transcriptional and non-transcriptional programmes
XH Fun, G Thibault
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019
52019
Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins
PTJ Shyu, BSH Ng, N Ho, R Chaw, YL Seah, C Marvalim, G Thibault
Sci Rep 9, 8637, 2019
42019
Lipid perturbation compromises UPR-mediated ER homeostasis as a result of premature degradation of membrane proteins
BSH Ng, P Shyu, R Chaw, SY Ling, G Thibault
bioRxiv, 178947, 2017
22017
A screen for mutants requiring activation of the unfolded protein response for viability
G Thibault, DTW Ng
Methods in enzymology 491, 199-216, 2011
22011
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Articles 1–20