Restoration of metabolic health by decreased consumption of branched‐chain amino acids NE Cummings, EM Williams, I Kasza, EN Konon, MD Schaid, BA Schmidt, ... The Journal of physiology 596 (4), 623-645, 2018 | 296 | 2018 |
Dopamine signaling in the dorsomedial striatum promotes compulsive behavior JL Seiler, CV Cosme, VN Sherathiya, MD Schaid, JM Bianco, ... Current Biology 32 (5), 1175-1188. e5, 2022 | 48 | 2022 |
GuPPy, a Python toolbox for the analysis of fiber photometry data VN Sherathiya, MD Schaid, JL Seiler, GC Lopez, TN Lerner Scientific reports 11 (1), 24212, 2021 | 46 | 2021 |
Enriching islet phospholipids with eicosapentaenoic acid reduces prostaglandin E2 signaling and enhances diabetic β-cell function JC Neuman, MD Schaid, AL Brill, RJ Fenske, CR Kibbe, DA Fontaine, ... Diabetes 66 (6), 1572-1585, 2017 | 43 | 2017 |
Complement 1q-like-3 protein inhibits insulin secretion from pancreatic β-cells via the cell adhesion G protein–coupled receptor BAI3 R Gupta, DC Nguyen, MD Schaid, X Lei, AN Balamurugan, GW Wong, ... Journal of Biological Chemistry 293 (47), 18086-18098, 2018 | 36 | 2018 |
Synergy Between Gαz Deficiency and GLP-1 Analog Treatment in Preserving Functional β-Cell Mass in Experimental Diabetes AL Brill, JA Wisinski, MT Cadena, MF Thompson, RJ Fenske, HK Brar, ... Molecular endocrinology 30 (5), 543-556, 2016 | 28 | 2016 |
The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice RJ Fenske, MT Cadena, QE Harenda, HN Wienkes, K Carbajal, ... Endocrinology 158 (6), 1645-1658, 2017 | 26 | 2017 |
A human pancreatic ECM hydrogel optimized for 3-D modeling of the islet microenvironment DM Tremmel, SD Sackett, AK Feeney, SA Mitchell, MD Schaid, E Polyak, ... Scientific reports 12 (1), 7188, 2022 | 23 | 2022 |
Systemic Metabolic Alterations Correlate with Islet-Level Prostaglandin E2 Production and Signaling Mechanisms That Predict β-Cell Dysfunction in a Mouse … MD Schaid, Y Zhu, NE Richardson, C Patibandla, IM Ong, RJ Fenske, ... Metabolites 11 (1), 58, 2021 | 18 | 2021 |
Ultrahigh-resolution mass spectrometry-based platform for plasma metabolomics applied to type 2 diabetes research Y Zhu, B Wancewicz, M Schaid, TN Tiambeng, K Wenger, Y Jin, ... Journal of proteome research 20 (1), 463-473, 2020 | 17 | 2020 |
Agonist-independent Gαz activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes MD Schaid, CL Green, DC Peter, SJ Gallagher, E Guthery, KA Carbajal, ... Journal of Biological Chemistry 296, 2021 | 14 | 2021 |
The EP3 Receptor/Gz Signaling Axis as a Therapeutic Target for Diabetes and Cardiovascular Disease MD Schaid, JA Wisinski, ME Kimple The AAPS journal 19, 1276-1283, 2017 | 14 | 2017 |
Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion HK Sandhu, JC Neuman, MD Schaid, SE Davis, KM Connors, R Challa, ... Pharmacology Research & Perspectives 9 (2), e00736, 2021 | 12 | 2021 |
A gene expression network analysis of the pancreatic islets from lean and obese mice identifies complement 1q like-3 secreted protein as a regulator of β-cell function JE Koltes, I Arora, R Gupta, DC Nguyen, M Schaid, J Kim, ME Kimple, ... Scientific Reports 9 (1), 10119, 2019 | 11 | 2019 |
GuPPy, a Python toolbox for the analysis of fiber photometry data. Sci. Rep. 11, 24212 VN Sherathiya, MD Schaid, JL Seiler, GC Lopez, TN Lerner | 8 | 2021 |
Prostaglandin EP3 receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance JA Wisinski, A Reuter, DC Peter, MD Schaid, RJ Fenske, ME Kimple American Journal of Physiology-Endocrinology and Metabolism 321 (4), E479-E489, 2021 | 5 | 2021 |
Chronically dysregulated corticosterone impairs dopaminergic transmission in the dorsomedial striatum by sex-divergent mechanisms AL Holloway, MD Schaid, TN Lerner Neuropsychopharmacology 48 (9), 1328-1337, 2023 | 4 | 2023 |
EP3 signaling is decoupled from the regulation of glucose-stimulated insulin secretion in β-cells compensating for obesity and insulin resistance MD Schaid, JM Harrington, GM Kelly, SM Sdao, MJ Merrins, ME Kimple Islets 15 (1), 2223327, 2023 | 2 | 2023 |
A role for EP3 and its associated G protein, Gz, in negatively regulating beta-cell function and mass in the context of insulin resistance and obesity A Reuter, JA Wisinski, D Peter, MD Schaid, RJ Fenske, ME Kimple bioRxiv, 671289, 2019 | 1 | 2019 |
The Molecular Mechanisms of Prostaglandin E2 Receptor 3 and its associated G protein, Gz, in the Pancreatic β‐cell MD Schaid, J Wisinski, E Laudre, M Kimple The FASEB Journal 31, 619.16-619.16, 2017 | 1 | 2017 |