Igor N. Berezovsky

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Enrico GuarneraPrincipal Scientist @ EMD Serono (Merck KGaA)Verified email at merckgroup.com
Alexander GoncearencoNCBI and NHGRI, NIHVerified email at nih.gov
Wei-Ven TeePost-doctoral Research Fellow, Bioinformatics Institute A*STARVerified email at bii.a-star.edu.sg
Eugene ShakhnovichProfessor of Chemistry Harvard UniversityVerified email at chemistry.harvard.edu
Zhen Wah TanBioinformatics Institute, A*STAR, SingaporeVerified email at bii.a-star.edu.sg
Tumanyan VladimirEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Laboratory of computationalVerified email at eimb.ru
Esipova Natalia GeorgievnaEngelhardt Institute of Molecular Biology RASVerified email at eimb.ru
Konstantin ZeldovichSanofi PasteurVerified email at sanofi.com
Simon MitternachtNRKVerified email at nrk.no
Frank EisenhaberBII A*STARVerified email at bii.a-star.edu.sg
Igor V KurochkinSysmex Co.Verified email at sysmex.co.jp
Dan S TawfikWeizmann Institue of ScienceVerified email at weizmann.ac.il
Birgit EisenhaberVerified email at bii.a-star.edu.sg
Nobuhiko TokurikiUniversity of British ColumbiaVerified email at msl.ubc.ca
Vladimir UverskyProfessor, USFVerified email at usf.edu
Christopher J OldfieldVirginia Commonwealth UniversityVerified email at vcu.edu
Alexander Y GrosbergProfessor of Physics, New York UniversityVerified email at nyu.edu
Fabian GlaserTechnion, Israel Institute of TechnologyVerified email at technion.ac.il
David BakerUniversity of WashingtonVerified email at uw.edu
Agnes Toth-PetroczyMPI of Molecular Cell Biology and Genetics and Center for Systems Biology DresdenVerified email at mpi-cbg.de

Igor N. Berezovsky

Senior Principal Investigator, Bioinformatics Institute, A*STAR, Singapore

Verified email at bii.a-star.edu.sg - Homepage

evolution of protein function allostery in proteins protein thermostability chromatin dynamics and epigenetic regulation


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Physics and evolution of thermophilic adaptation IN Berezovsky, EI Shakhnovich Proceedings of the National Academy of Sciences 102 (36), 12742-12747, 2005	308	2005
Protein and DNA sequence determinants of thermophilic adaptation KB Zeldovich, IN Berezovsky, EI Shakhnovich PLoS computational biology 3 (1), e5, 2007	298	2007
Allostery in its many disguises: from theory to applications SJ Wodak, E Paci, NV Dokholyan, IN Berezovsky, A Horovitz, J Li, ... Structure 27 (4), 566-578, 2019	248	2019
Do viral proteins possess unique biophysical features? N Tokuriki, CJ Oldfield, VN Uversky, IN Berezovsky, DS Tawfik Trends in biochemical sciences 34 (2), 53-59, 2009	228	2009
Closed loops of nearly standard size: common basic element of protein structure IN Berezovsky, AY Grosberg, EN Trifonov Febs Letters 466 (2-3), 283-286, 2000	184	2000
Positive and negative design in stability and thermal adaptation of natural proteins IN Berezovsky, KB Zeldovich, EI Shakhnovich PLoS Computational Biology 3 (3), e52, 2007	137	2007
Insulin-degrading enzyme in the fight against Alzheimer’s disease IV Kurochkin, E Guarnera, IN Berezovsky Trends in pharmacological sciences 39 (1), 49-58, 2018	136	2018
Allosteric sites: remote control in regulation of protein activity E Guarnera, IN Berezovsky Current opinion in structural biology 37, 1-8, 2016	122	2016
A dominant negative heterozygous G87R mutation in the zinc transporter, ZnT-2 (SLC30A2), results in transient neonatal zinc deficiency I Lasry, YA Seo, H Ityel, N Shalva, B Pode-Shakked, F Glaser, B Berman, ... Journal of Biological Chemistry 287 (35), 29348-29361, 2012	108	2012
Entropic stabilization of proteins and its proteomic consequences IN Berezovsky, WW Chen, PJ Choi, EI Shakhnovich PLoS computational biology 1 (4), e47, 2005	108	2005
Structure-based statistical mechanical model accounts for the causality and energetics of allosteric communication E Guarnera, IN Berezovsky PLoS computational biology 12 (3), e1004678, 2016	104	2016
Distinct stages of protein evolution as suggested by protein sequence analysis EN Trifonov, A Kirzhner, VM Kirzhner, IN Berezovsky Journal of molecular evolution 53, 394-401, 2001	96	2001
Van der Waals locks: loop-n-lock structure of globular proteins IN Berezovsky, EN Trifonov Journal of Molecular Biology 307 (5), 1419-1426, 2001	92	2001
AlloSigMA: allosteric signaling and mutation analysis server E Guarnera, ZW Tan, Z Zheng, IN Berezovsky Bioinformatics 33 (24), 3996-3998, 2017	91	2017
SPACER: server for predicting allosteric communication and effects of regulation A Goncearenco, S Mitternacht, T Yong, B Eisenhaber, F Eisenhaber, ... Nucleic acids research 41 (W1), W266-W272, 2013	87	2013
Binding leverage as a molecular basis for allosteric regulation S Mitternacht, IN Berezovsky PLoS computational biology 7 (9), e1002148, 2011	84	2011
Evolutionary aspects of protein structure and folding EN Trifonov, IN Berezovsky Current opinion in structural biology 13 (1), 110-114, 2003	74	2003
On the perturbation nature of allostery: sites, mutations, and signal modulation E Guarnera, IN Berezovsky Curr. Opin. Struct. Biol 56, 18-27, 2019	67	2019
Simple yet functional phosphate-loop proteins ML Romero Romero, F Yang, YR Lin, A Toth-Petroczy, IN Berezovsky, ... Proceedings of the National Academy of Sciences 115 (51), E11943-E11950, 2018	67	2018
Loop fold structure of proteins: resolution of Levinthal's paradox IN Berezovsky, EN Trifonov Journal of Biomolecular Structure and Dynamics 20 (1), 5-6, 2002	63	2002

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